RELAPSE. RESISTANT OR REFRACTORY ABSCESS

Analysis of case reports of 'Relapse' of amoebic liver abscess
Author	No. of cases	Treatment Initial regime	Dosage	Asymptomatic period before relapse	Treatment Second regime	Dosage	Remarks
Sodeman et al ²²	1	Emetine	65 mgm. OD for 8 days	2 months	Chloroquine	0.6 G. base/day for 2 days 0.3 G. base/day for 19 days.	Recovered
Rao et al ²¹	1	Metronidazole with aspiration	800 mgms. tds. for 10 days	2 weeks	Emetine + chloriquine	Emetine 60 mg./day for 6 days Chloriquine 3 weeks	Recovered
Powell et al ²⁰	2 (Out of 25 cases)	Ambilhar	500 mgm. bid. or tds. (1.5 mgm/kg) for 10 days	3 months and 6 months	Dehydroemetine	Not mentioned	Recovered
Manson-Bahr ¹⁴	1	Emetine + EBI + Chloriquine + aspiration	Emetine 60 mgm. OD for 7 days followed by EBI 1.26 G. in 7 days with aspiration followed by chloriquine 4 G. base over 8 days. 0.75 G. on 1st day 0.3 G./day as maintenance	10 days	Chloriquine further dosage with aspiration	4.75 G. base over 16 days.	Recoveres
Crane et al⁶	3 (out of 200 cases)	One treated with chloriquine + surgical drainage Two treated with chloriquine + aspiration	12.9 G. base over 10 days. 10.86 G. base over 10 days	3 months or more	- Not mentioned	- Not mentioned	- Not mentioned