In the past the
diagnosis of amoeboma was made very frequently.
Majority of the time the diagnosis was made in the
surgical wards It is the surgeons who have encouraged
this label because the surgeons always want to label
any "lump" which they feel anywhere in the
body.
Patients having
symptoms of dysentery and having a lump in the right
iliac fossa were diagnosed to have amoeboma of the
caecum. Similar patients, who had a lump felt on
rectal examination, were diagnosed to have a rectal
"amoeboma"
The above two
diseases do not exist. It is surprising that the
latest Oxford Textbook or Medicine (1995 edition)
continues mentioning the existence of this disease
(as usual the authors have copied from the old
edition).
Based on my
experience of witnessing hundreds of autopsies of
patients who have died of amoebiasis, [1] I have proved that the
above two entities do not exist. The lump which the
surgeons feel in the right iliac fossa in the case of
amoebic dysentery, is the inflammatory mass
comparable to appendicular mass. The whole caecum is
so inflamed that often there is a leak and localised
peritonitis occurs and a lump forms.
Quite often in
the past the surgeons used to "open up"
these patients. The colon on the operation table was
so friable, that invariably these patients died post
operatively of faecal peritonitis (in private
hospitals autopsies are not conducted). The surgeons
operate with the idea that because of Ba enema
appearance, there must be some amoebic granuloma of
the caecum, and they will try to resect the same as
in a case of malignancy of the caecum, which is a
differential diagnosis of amoeboma.
These patients
will invariably respond to medical treatment and
should be treated conservatively, exactly like an
appendicular mass. If the Surgeons make the diagnosis
of "amoeboma", I can challenge that if the
colonoscope
which is made
available for investigations (which was not available
in olden days) is inserted, nothing will be seen in
the caecum except a marked oedematous amoebic
inflammation of the mucosa !! (though inserting a
colonoscope in a very friable colon may not be safe).
Coming to the
rectum; caecum and rectum are the most affected areas
in the amoebiasis. The amoebic inflammation is so
marked in the rectum, that because of the oedema of
the mucous membrane, often "pseudo polyps"
get formed. (like ulcerative colitis). These are the
pseudo polyps which are being felt by the surgeons
and although no autopsy reports are ever been
reported as "granuloma". the surgeons
continue to call it amoebic granuloma which responds
dramatically to a few injections of emetine!
It is high time
that the gastroenterologists in India with the help
of modern imaging and serological tests and invasive
procedures prove to the world that these entities do
not exist and write to the editors of Oxford Textbook
of Medicine to delete this disease and not misguide
the future young budding post graduates!
REFERENCES
1. OP
Kapoor. BN Nathwani, VR Joshi. Amoebic Peritonitis.
Journal of Tropical Medicine and Hygiene, Jan 1972.
75: 11-15