1. Role of magnesium in type II diabetes
Namita Patil, Anand Gokani, Sonia |
Magnesium though a micronutrient should be supplemented
to patient with type II diabetes, low plasma magnesium
level have been found to be associated with insulin resistance.
This is an analysis made from case study of six patients
to focus on a concept which is so far neglected. All these
patients with type II DM without considering age, sex
had low magnesium level. Some are on the borderline and
the insulin requirement were high.
Magnesium correction through food item rich in green leafy
vegetable, fruits and nuts or supplements about 30 mg/day
can lead to good magnesium levels intracellularly as well
as extracellularly and induce the requirement of insulin
to some extent in diabetic type II. |
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2. Typha angustata (TA) : An important aeroallergen
from Mumbai (India) City
UD Mahadik-Salvi, PV Niphadkar, HL Dhar |
Typha angustata (TA), a ubiquitous weed exhibit monoporous
pattern under scanning electron microscopy. Aerobiological
studies in Mumbai showed the high prevalence of pollens
of TA among the predominant aeroallergen. Patients having
sensitivity to pollen allergen of TA were subjected to
estimation of total, allergen specific IgE and nasal provocation
test (NPT). 559 patients with allergic rhinobronchitis
were investigated for eosinophilia, SPT, PFT, RT. Out
of which, 38 (6.8%) patients gave strong positive response
to TA 16 out of 20 patients showed strong positive response
when challenged with TA in NPT. The pollen extract of
TA resolved into 21 Coomassie blue-stained bands. Of these,
nine protein components of TA pollen extract with molecular
weights of 82,75,49,42,36,33,27,23 and 14 kDa were recognized
by 90% of the patients sera tested on immunoblot. The
present study establishes the allergenic important of
TA pollen grains. |
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3.Allergenicity of food and aeroallergens in urticaria
SV Joshi, DM Tripathi, SM Sawant, HL Dhar |
Urticaria, commonly known as hives which is allergic
reaction to foods, medicines and environmental substances.
It is characterized by development of itchy welts or wheals
varying in size. This reaction in upper epidermis is vascular
in nature. Sporadic reports are documented in literature
regarding very few aeroallergens in atopic dermatitis.
Purpose of this work is to study the significance of food
and aeroallergens in urticaria.
The study comprises 100 consecutive cases (47 males, 53
females) of urticaria. They were divided into two groups
: non-vegetarians (65) and vegetarians (35). In both the
groups reactions were equal to various offending food
stuff as well as aeroallergens. Strong reactions (3+ —
4+) to pineapple, tamarind and yeast were significantly
higher in vegetarians. Non-vegetarians showed higher sensitivity
to legumes and seafood. Interesting observation of the
study is that sensitivity to fungi (3+ — 4+) was
(41.54%), house dust (40%), house dust mites (40%), was
significantly higher in non-vegetarians. Amongst fungi,
sensitivity to Candida albicans (15.38%) was highest followed
by various species of Aspergillus viz tamari, fumigatus
and niger (9.23%, 7.69%, 7.69% respectively), Rhizopus
nigricans (9.23%), Curvularia lunata (9.23%), Penicillum
(9.23%), Fusarium solani (6.15%) Alternaria (4.61%), Cladosporium
herbarum (4.61%). Predominant pollen were : Parthenium
(15.38%), Xanthium stromarium (9.23%) Prosopis julifera
(7.69%), Cocos nucifera (6.15%). The study strongly suggests
the need to incorporate aeroallergens in panel of commercial
extracts of allergens employed for diagnosis and are of
therapeutic importance. |
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4. Improved asthma control with treatment of Helicobacter
pylori + GERD
KS Menon, S Shyamsundar, SM Sawant, HL Dhar |
Silent gastroesophageal reflux disease (GERD) coexists
with and worsens asthma by multiple mechanisms. Role of
H. pylori in GERD is controversial. A recent report suggests
that eradication of H. pylori reduces recurrence rates
of GERD. Serologic and case control studies have shown
that H. pylori infection may be associated with development
of chronic bronchitis. The aim of this study was to study
the effect of treatment for H. pylori in moderate persistent
asthma.
Treatment for H. pylori results in significant improvements
in peak flow rates compared to standard therapy in moderate
persistent asthma, even in patients with no dyspepsia.
H. pylori infection may be common in asthmatics, and worsen
airway disease. Treatment for H. pylori may result in
improved early asthma control. |
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