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The Role of 10% Xylocaine Spray for
Bronchoscopy in Paediatric Patient for Removal of Foreign Body
M Sarkar*, Pallavi Nandoskar** |
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10% Xylocaine spray was used as an adjunct
to IV Ketamine in 100 patients undergoing bronchoscopy for removal
of foreign body from tracheobronchial tree. The effect of xylocaine
on this procedure was judged as good in 60 patients, fair in
30 patients and poor in 10 patients. The last 10 patients required
additional dose of suxamethanium chloride, one patient had shown
fall in O2 saturation and had cardiac arrest on table for which
patient was kept in ICU for ventilatory support in post operative
period for 24 hrs. No other life threatening complications were
seen in any other patient. So it was concluded that 10% Xylocaine
spray facilitates the smooth performance of Bronchoscopy.
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| INTRODUCTION |
Exogenous foreign bodies in tracheobronchial tree particularly
in children are common and challenging emergency for anaesthesiologist,
paediatrician and otolaryngologist too. Common objects
which may be inhaled are groundnut seeds, tamarind seeds,
chikoo seeds, metallic pins1 etc. Normal protective cough
reflexes prevent aspiration of these objects but occasionally,
this reflex which is available to prevent foreign body
from going in laryngotracheo bronchial tree, is not effective.
The performance of bronchoscopy for removal of foreign
body, general anaesthesia is required. Though no ideal
method has yet been developed for the same, the use of
IV lignocaine together with Thiopentone for this purpose
was recorded by Blancato et al.2 The depression of cough
reflex by IV lignocaine, was demonstrated by Steinhouse
et al.5 Steinhouse said, `lignocaine obtunds the pharyngeal
and laryngeal reflexes without causing respiratory depression'.
De, Clive louse et al have reported the use of IV lignocaine
to provide analgesia. We decided to do a study of xylocaine
spray with Ketamine, N2O; O2 and suxamethanium for bronchoscopy,
for removal of foreign bodies in paediatric patients. |
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| Material and Methods |
he prospective study was carried out in ENT Theatre
at Seth GS Medical College and KEM Hospital and RN Cooper
Hospital, Mumbai, in 100 patients and the age of the patients
was less than 10 yrs.
Exclusion criteria was patients with lung complications
like pneumonitis, atelectasis, pulmonary suppuration empyema,
age less than 6 months.
Different types of FB were found are:-
- Pea nuts
- Chana
- Whistle of toys.
- Different kind of fruits.
- Rathi seeds and
- Safety Pins.
All patients underwent a thorough clinical examination
with minimum Investigations like Hb/CBC, X-ray chest and
ABG.
All the patients were premedicated with injection Glycopyrolate
in the doses of 4 µg/kg; patients were wheeled into
operation theatre, monitors were attached.
IV Isolyte P drip was started; patients were oxygenated
with 100% oxygen for 3 minutes then general anaesthesia
was begun with IV Ketamine 1-2 mg/kg body weight, 10%
Xylocaine was sprayed after induction of anaesthesia.
Scoline was introduced in the dosage 1-2 mg/kg body weight,
as soon as twitches went off bronchoscopy was performed.
During the procedure anaesthesia was maintained with the
help of O2 + N2O and intermittent halothane, through a
side arm of bronchoscope. Additional doses of intermittent
scoline was injected IV as and when required, light plane
of Anaesthesia was observed. During the entire procedure
the pulse rate, BP, O2 saturation was monitored, ABG was
done before and after the procedure. After the procedure
patients were monitored till they became fully conscious
and shifted to recovery room. They were observed for cyanosis,
laryngospasm, bronchospasm and coughing.
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| Results |
Results were considered good if the patient has shown
no significant changes in vital signs during bronchoscopy
and the procedure could be performed with ease.
Results were considered as fair if the patient has shown
changes in vital parameters and O2 saturation but within
acceptable limits and bronchoscopy procedure was performed
without difficulty.
It was considered as poor if there were some complications
like bucking, coughing, laryngospasm which hampered bronchoscopy
and needed some anaesthetic assistant.
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Demographic data Table 1 suggesting maximum number of patients belonging to age group of 6 months to 2 years of age. Next common age for foreign body was 2 to 4 years as shown in Table 2. The incidence of foreign body was going down as children were growing. |
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| Observation |
As per out study results were good in 60 patients.
Table 3 the fair group of 30 patients have shown change
in pulse rate of 10-20 beats/min. Average fall in O2 in
saturation was observed between 10-20%, average change
in blood pressure was 10-20 mm of Hg. In poor group 10
patients had complications like stridor, bucking and laryngospasm
which needed extra dose of suxamethanium. Out of 10 patients
one patient had cardiac arrest at the time of removal
of foreign body, and reviewed. Shifted to ICU for ventilatory
support and ICU care. Post operatively 4 patients had
severe cough. Blood gas analysis did not reveal any hypercarbia
or hypoxia. |
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| Discussion |
The difficulties in diagnosis of foreign body in children
include nonavailability of history or out of fear, absence
or lack of clinical or radiological signs.
Bronchoscopy is a delicate procedure, evokes a series of
unpleasant reflexes which may make examination difficult.
The aim of ketamine anaesthesia with xylocaine is to suppress
laryngopharyngeal reflexes and permit bronchoscopy, simultaneously
advantage of bronchodilatory effect of these two drugs were
taken into consideration. Vigorous coughing can lead to
unwanted complications like rupture of trachea, xylocaine
suppresses the laryngopharyngeal reflexes which is a side
effect of ketamine anaesthesia, without causing respiratory
depression. Ketamine provides a potent analgesia.
Advantages of lignocaine as an adjunct during Bronchoscopy
are as follows, suppression of cough reflexes, relaxation
of larynx, elimination of post operative cough, potent analgesia,
antiarrhythmic and bronchodilator effect. |
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| Conclusion |
| According to this study it was concluded that 10% Xylocaine
spray helps to facilitate and smoothen the performance of
bronchoscopy, in paediatric age group patients, along with
ketamine anaesthesia. |
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| Acknowledgements |
| I am thankful to Madam Dean Dr. N Kshirsagar for permiting
us to publish this article and we are thankful to Madam
Dr. LS Chaudhari for her guidance. |
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| References |
| 1. |
Kirtane MV, Shah KL. Foreign bodies
in bronchi. Post Graduate Journal 1984; 30 (4) : 219-23. |
| 2. |
Huber FC, Reves IV, Liutierrez J, et
al. Ketamine its effect an airway resistance in man.
South Med J 1972; 65 : 1176. |
| 3. |
Fischer MM. Ketamine hydrochloride
in severe Bronchospasm. Anaesthesia 1977; 32 : 771. |
| 4. |
Lidocaine plasma conc. in paediatric
patients provides airway topical anaesthesia from
a calibrated device. Anaesth Analg 1996; 82 (5) :
1003-6. |
| 5. |
Open Surgical removal of JB, FB a case
report. J Paed Surg 1998; 33 (5) : 776-7 Med 9607499. |
| 6. |
Blan Kato LS, Pany ATC,
Alarsab D. IV Lidocaine as an adjunct to GA for endoscopy
anaesthe and analges. 1969; 43 : 224-27. |
| 7. |
De Cline-Louse, SG Desmond J, North
J. IV Lignocaine. Anaesthesia 1958; 13 : 138-46. |
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COMPRESSING ISSUE
‘Malignant spinal-cord compression
is a common complication of cancer and has a substantial
negative effect on quality of life and survival....
it continues to be a perplexing problem that commonly
needs rapid decision making on the part of several
specialists’
Evidence suggests that 2.5-5.0% of patients
with terminal cancer have epidural spinal-cord
compression in the last 2 years of illness, and
that 4.0-5.5% of children with cancer also develop
spinal-cord compression. Furthermore, despite
widespread availability of good diagnostic technology,
most patients are diagnosed only after they become
unable to walk. Moreover, compression of the spinal
column is a common presenting sign of non-Hodgkin
lymphoma and myeloma. In the January issue of
The Lancet Oncology, Dheerendra Prasad and David
Schiff review the epidemiology, pathophysiology,
and clinical features of malignant spinal-cord
compression and, in particular, they discuss the
role of surgery and radiotherapy in the management
of these patients.
Lancet Oncol 2005; 6 : 15-24.
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| *Associate Professor; **Registrar, Department of Anaesthesia, KEM Hospital Parel. |
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